Use an antibody validated in CUT&Tag for best chance of success. For your convenience, EpiCypher offers an array of CUT&Tag validated antibodies for histone post-translational modifications (PTMs).
If your target has not been validated in CUT&Tag, you can try an antibody that has been validated in CUT&RUN. Although we cannot guarantee that CUT&RUN antibodies will work in CUT&Tag, they are a good starting point as they have also been rigorously tested by EpiCypher.
If we do not carry a CUT&Tag or CUT&RUN validated antibody for your target, you will need to validate antibodies from external vendors or contact us for recommendations. We recommend testing at least three antibodies; see other articles in this section for guidance.