Can I use other vendors' library prep kits?

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While some other vendors’ library prep kits are compatible with CUT&RUN DNA, the CUTANA™ CUT&RUN Library Prep Kit (EpiCypher 14-1001) is specifically designed to accommodate low input samples and preferentially amplify CUT&RUN-sized fragments. We have found that other kits often require modifications to their protocol in order to obtain similar results. If you have another library prep kit that you would like to use, please reach out to us at techsupport@epicypher.com to check if your kit is compatible and to receive information on recommended modifications to your kit’s protocol.