--- title: "What types of sequencing files are compatible with CUTANA™ Cloud?" slug: "what-types-of-sequencing-are-compatible-with-cutana-cloud" updated: 2026-11-13T17:05:28Z published: 2025-08-27T15:43:19Z canonical: "support.epicypher.com/what-types-of-sequencing-are-compatible-with-cutana-cloud" --- > ## Documentation Index > Fetch the complete documentation index at: https://support.epicypher.com/llms.txt > Use this file to discover all available pages before exploring further. # What types of sequencing files are compatible with CUTANA™ Cloud? CUTANATM Cloud supports paired-end sequencing files in fastq.gz or unzipped fastq format. Paired-end sequencing improves data fidelity over single-end sequencing, enabling high-quality alignment in repetitive DNA regions and generating long contigs for *de novo* sequencing by bridging gaps in the consensus sequence. CUTANATM Cloud currently only supports paired-end sequencing.