---
title: "What is 'CUTANA Spike-In 2'?"
slug: "what-is-cutana-spike-in-2"
updated: 2025-08-27T15:43:50Z
published: 2025-08-27T15:43:50Z
canonical: "support.epicypher.com/what-is-cutana-spike-in-2"
---

> ## Documentation Index
> Fetch the complete documentation index at: https://support.epicypher.com/llms.txt
> Use this file to discover all available pages before exploring further.

# What is 'CUTANA Spike-In 2'?

Bench scientists can save time and money on experimental controls by adding multiple spike-ins to a single IgG control reaction. This allows a single reaction to be searched for two different CUTANATM Spike-in barcode sets, producing two output reactions from one input. To avoid duplicate reaction identities in the outputs, the pipeline will append the name of the analyzed spike-in to the Short Name of both outputs.