---
title: "What CUT&RUN antibodies does EpiCypher offer?"
slug: "what-cut-and-run-antibodies-does-epicypher-offer"
description: "Explore EpiCypher's CUT&RUN-validated antibodies for histone PTMs, transcription factors, chromatin proteins, and epitope tags."
updated: 2026-02-27T15:27:07Z
published: 2026-02-27T15:27:07Z
canonical: "support.epicypher.com/what-cut-and-run-antibodies-does-epicypher-offer"
---

> ## Documentation Index
> Fetch the complete documentation index at: https://support.epicypher.com/llms.txt
> Use this file to discover all available pages before exploring further.

# What CUT&RUN antibodies does EpiCypher offer?

> This article also applies to Multiomic CUT&RUN.

EpiCypher offers a collection of antibodies proven to generate robust CUT&RUN profiling data. Visit our [antibodies complete list](https://www.epicypher.com/antibodies-complete-list/) for the most up-to-date list.

We continue to investigate additional antibodies for high-quality performance in CUT&RUN. Below we outline the lot-specific testing criteria for EpiCypher CUTANA™ CUT&RUN antibodies for various target classes.

- **Chromatin-associated protein targets:** We offer CUT&RUN antibodies to transcription factors (e.g. CTCF), chromatin reader proteins (e.g. BRD4), modifying enzymes (e.g. MLL1), and remodelers (e.g. SMARCA2, SMARCA4). Each antibody displays high signal-to-noise in CUT&RUN and generates genomic distribution profiles consistent with the reported function of the target protein (for example, DNA binding motif analysis for transcription factors).
- **Epitope-tagged protein targets:** Our antibodies to HA- and DYKDDDDK-tagged proteins are validated in CUT&RUN using defined SNAP-CUTANA™ Spike-in Controls. See [this blog](https://www.epicypher.com/resources/blog/controls-for-epitope-tags) for more information about these antibodies, their spike-in controls, and how they can be used for robust CUT&RUN profiling.
- **Histone PTM targets:** Histone PTM antibodies are particularly susceptible to off-target binding, which can compromise biological interpretations. To address these problems, EpiCypher developed the SNAP-CUTANA K-MetStat Panel (EpiCypher 19-1002), and is using these defined nucleosome spike-in controls to identify best-in-class histone lysine methylation PTM antibodies for CUT&RUN. [This strategy](/v1/docs/using-snap-cutana-spike-in-controls-for-histone-ptm-antibody-validation) is the only method that directly confirms antibody specificity in CUT&RUN against physiological on- and off-target substrates. We also validate antibody efficiency, allowing users to be confident when using reduced cell numbers. Each of our SNAP-Certified™ Antibodies show:
  - High specificity: <20% recovery of off-target PTMs in the K-MetStat Panel.
  - High target efficiency: Robust profiling at 500,000 and 50,000 starting cells.