---
title: "Can I use this kit to prepare CUT&RUN libraries for transcription factors?"
slug: "can-i-use-this-kit-to-prep-cutrun-libraries-for-transcription-factors"
updated: 2025-11-25T20:45:53Z
published: 2025-11-25T20:45:53Z
canonical: "support.epicypher.com/can-i-use-this-kit-to-prep-cutrun-libraries-for-transcription-factors"
---

> ## Documentation Index
> Fetch the complete documentation index at: https://support.epicypher.com/llms.txt
> Use this file to discover all available pages before exploring further.

# Can I use this kit to prepare CUT&RUN libraries for transcription factors?

Yes, this kit can be used to prepare CUT&RUN libraries from any target and does not require special modifications for transcription factors. However, you may find that modifications during the CUT&RUN protocol itself may help to improve your signal for transcription factors; for details, check out [this article.](/v1/docs/cut-and-run-adjust-for-protein-targets)